Why Mayo Clinic
The Research shield at Mayo Clinic is committed to creating a diverse environment and recognizes that diverse research teams make better decisions, are more equipped to solve complex problems and adapt to change, and produce better outcomes. That diversity is about opening up to unconventional ideas that create better outcomes, while recognizing colleagues' unique contributions. Become part of the legacy that embraces these differences and enables us to provide the best care to patients from all over the world.

Mayo Clinic offers a variety of employee benefits. For additional information please visit Mayo Clinic Benefits. Eligibility may vary.

Position description
There is an open, fully-funded postdoctoral position at Mayo Clinic (Rochester, MN) in the laboratory of Michael F. Romero, PhD, a Professor in the Departments of Physiology & Biomedical Engineering and Nephrology & Hypertension in collaboration with Aleksey Matveyenko, PhD (Physiology & BME and Regenerative Medicine). This position is in support of a new collaborative NIH grant: R01-DK128844 - Role of pH-mediated metabolic reprogramming in cell failure in Type 2 Diabetes Mellitus. The foundational work for this is:
Brown, MR, Holmes, H, Rakshit, K, Javeed, N, Her, TK, Stiller, AA, Sen, S, Shull, GE, Prakash, YS, Romero, MF*, and Matveyenko, AV*. (2021) Electrogenic sodium bicarbonate cotransporter NBCe1 regulates pancreatic cell function in type 2 diabetes. The Journal of Clinical Investigation 131, e142365; https://www.ncbi.nlm.nih.gov/pubmed/34623331
We seek to recruit a highly motivated cellular and molecular biologist OR physiologist with interests in ion / solute transport and diabetes or pancreas regeneration. Mayo Clinic values and promotes team-science. This collaborative project will focus on acid-base transporters (H+ and HCO3 transporters) in pancreatic -cells. The project is envisioned to use a combination of cellular imaging and electrophysiology with mouse and human pancreatic islets in diabetes. Research in the Romero lab focuses on ion and solute transport but spans molecular biophysics, cell and tissue transport, organ physiology and animal models (Drosophila, Xenopus, zebrafish, mouse, dog) as well as human tissue models. Work in the Matveyenko lab is focuses on type 2 diabetes and particularly beta-cell biology and physiology, e.g., circadian rhythms, genes and signaling pathways defining beta-cell function, islet biology, regeneration of pancreatic beta-cells.

Interested applicants should send (a) Biosketch / CV, (b) names of 2-3 professional references and (c) a 1-2 paragraph statement of professional goals to: Michael F. Romero, PhD; Romero.michael@mayo.edu

A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.

The following is required for completeness of application:

• Current curriculum vitae with bibliography

• Proof of doctoral degree (copy of diploma or final transcript with English translation, if applicable) or a letter from your university's Registrar office indicating you have fulfilled all doctoral program requirements and are eligible to graduate.

Please also be prepared that you may be asked to provide three letters of recommendation to the hiring PI prior to an interview.

Qualifications
Must have a Ph.D., M.D., or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship, at Mayo Clinic or elsewhere.

PhD must have been acquired no earlier than 2020. Strong English presentation and writing skills required. Record required of first author publication in the fields of biochemistry, molecular or cellular biology, pharmacology or physiology, published or accepted for publication into peer-reviewed journal.


Benefits eligible
Yes

Schedule
Full Time

International Assignment
No

Site description
Mayo Clinic is located in the heart of downtown Rochester, Minnesota, a vibrant, friendly city that provides a highly livable environment for more than 34,000 Mayo staff and students. The city is consistently ranked among the best places to live in the United States because of its affordable cost of living, healthy lifestyle, excellent school systems and exceptionally high quality of life.

Recruiter
Kara Schott